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The Transition Towards Single-use Bioreactors

Roots Analysis has announced the addition of the “Single-use Bioreactors, 2014-2024” report to their offering. The report provides an extensive study of this emerging field, including detailed sales forecast of single-use bioreactors in the coming decade. In addition to the market forecasts, the report clearly identifies the various challenges and opportunities in the short and long term. It provides a comprehensive analysis of the market including profiles of ten established and emerging companies. Mayank Kaura, the lead analyst, said, “Single-use bioreactors are already being deployed for high density cell culture applications (monoclonal antibodies, recombinant proteins, vaccines etc.). Newer application areas being researched include stem cells and personalised medicine.” “We identified 17 manufacturers offering around 80-90 models of single-use bioreactors with working volumes ranging from as low as few millilitres to up to 2000L. Quite recently, many start-ups have sprung up. Examples include CerCell, PBS Biotech, Cellexus Limited; these start-ups have launched single-use bioreactors with innovative features and are likely to play an increasingly important role in the future.”

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Antibody Drug Conjugates: Contract manufacturing market to evolve rapidly, predicts Roots Analysis

Roots Analysis has announced addition of the “Antibody Drug Conjugates: Contract Manufacturing Market, 2014-2024” report to their offering. The report provides an extensive study of the contract manufacturing opportunity for this emerging class of therapeutics. It identifies various CMOs active in this space, their capabilities with respect to ADCs, available capacity (clinical/commercial) for bio-conjugation and geographic location/spread of the facilities. Shivani Singh, the principal analyst, said, “The multi-component aspect of ADCs deems it necessary to have both biologic and high-potency facilities. Despite the fact that this new class of therapeutic agents is gaining increased attention, in-house manufacturing of these molecules is rare.” “Most of the companies have limited number of ADCs under development. Considering that utilisation rates are likely to be low in near future, the investment required for setting up in-house high-containment biologic facilities is a huge financial risk. As such, majority of the work is currently being outsourced.”

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